Well you kind of have to see the talk stuff come out. A lot of stories revolve around it and not just shounen titles. It's really just a part of being a story, if a character doesn't really try to get his point across it just leaves things dry.
I'm guessing since Madara was revived using the wrong jutsu, this will be the cause of his defeat. Maybe Kishimoto will end up recreating the Valley of the End fight as the series ending, but this time with Sasuke and Naruto. The series ends with both killing each other, a sad ending with them proclaiming their friendship (no yaoi ).
Kishimoto tends to take the easy way out complicated story lines. Example, revive every dead character when Pein invaded or creating Izanami to defeat the undefeatable Izanagi. Killing them both will get rid of the pairing aspect everyone keeps looking forward to.
Tsunade won't die, but she will be crippled after this war is over. She probably won't be able to walk anymore. She'll be using a wheelchair. She won't be in physical shape to remain as Hokage.
________________ ............Naruto Girls...........You Gotta Love Em'