Misako Rocks! developed a love for comics and manga at an early age and drew her first comic at the age of 13. She moved to New York in 2001 and worked as a a puppeteer, face painter, animal balloon maker, and art teacher while still developing her own work. Her first break came when the Onion decided to use her illustrations for their now famous "Savage Love" column, which runs every week. Shortly thereafter, Misako scored a two-book deal with Hyperion, a three-book deal with Henry Holt and a writing gig for Archie comics.

She has been featured in many magazines and newspapers, including Elle Girl and the New York Times. The BBC and NHK also featured her in a documentary about her comic book life.

Misako currently lives in Brooklyn, New York and spends her free time riding her vintage bike, making hip hop, kissing babies, shaking hands, slam dunking and eating lots of Onigiri !!!