Unlike his earlier creation, Whimsical Orange Road, Matsumoto Izumi's Sesame Street is more grounded in reality. There is no one with special powers, no mysterious people with questionable pasts, no outrageous plots. In many ways, Sesame Street is more whimsical than Orange Road.

This strict adherence to reality is no accident. The author nicknames his work a "Downtown Comedy". The setting for this comic is in the heart of Tokyo, one of Japan's most congested cities. Many of the plots are derived from real life problems common in Japan. For example, half the second volume is about a "Jiageya" who cheats the family out of their home. "Jiageya" literally means "Land Snatcher", a derogatory term for land speculators who cheat people of their land and reap huge profits from the impacted real estate market.