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Sakuranbo Syndrome  
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"Progressive Rejuvenation Syndrome." This is an extremely rare disease causing the inflicted person to gradually become younger. The main character of this story, Munenori Agawa, is the only person that could save Rena Amami from this odd disease. Agawa's saliva is the only thing that can halt the disease from making Rena younger, so they must kiss everyday in order for her to survive. This causes an immense amount of conflict and drama between Agawa and his new girlfriend, Sayako Asou. This triangle relationship story tests the capabilities and limitations of human love.


Related Series

Associated Names
丘比特的恶作剧Ⅱ 櫻桃症候群
Cupid No Itazura 2 Cherry Syndrome
Cupid No Itazura 2 Sakuranbo Syndrome
Cupid's Prank 2: Cherry Syndrome
Cupid's Prank II: Cherry Syndrome

Groups Scanlating
Ciel Scans
Lemon Scans
Manga Pirate

Latest Release(s)
v.11 c.95 (end) by Norway Scan & Ciel Scans & Lemon Scans over 2 years ago
v.11 c.94 by Norway Scan & Ciel Scans & Lemon Scans over 2 years ago
v.11 c.93 by Norway Scan & Ciel Scans & Lemon Scans over 2 years ago
Search for all releases of this series

Status in Country of Origin
11 Volumes (Complete)

Completely Scanlated?

Anime Start/End Chapter

User Reviews

4 topics, 17 posts
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User Rating
Average: 8.4 / 10.0 (406 votes)
Bayesian Average: 8.26 / 10.0
 31% (124 votes)
 22% (90 votes)
 24% (98 votes)
 14% (58 votes)
 3% (14 votes)
 1% (5 votes)
 1% (3 votes)
 0% (1 votes)
 0% (2 votes)
 3% (11 votes)

Last Updated
September 10th 2017, 12:39pm PST



Category Recommendations





Original Publisher

Serialized In (magazine)
Young Sunday (Shogakukan)

Licensed (in English)

English Publisher

Activity Stats (vs. other series)
Weekly Pos #353 increased(+104)
Monthly Pos #515 decreased(-88)
3 Month Pos #499 increased(+26)
6 Month Pos #495 increased(+62)

List Stats
On 1894 reading lists
On 1092 wish lists
On 628 completed lists
On 63 unfinished lists
On 408 custom lists

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Forum Posts
Ending 3 months ago
To Whom I needs to pay to these series moved on? over 5 years ago
why lagged behind? over 6 years ago
Hesitant to open file over 7 years ago

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User Comments [ Order by usefulness ]

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No it's Not a Rushed Ending... a Good Romance by the Way!   
Rating: 9.0 / 10.0
by Xiximaro
October 19th, 2017, 4:09pm
The user below me said the ending was rushed, I don't agree... The story just didn't had more to offer and the author really did a good job coming up with the story till the end and he done this without dragging which nowadays it's rare. And why do a last arc of the size it was if the ending was going to be rushed? The author didn't change magazine cause he was ending the story.

A person might think the ending was rushed cause usually the pattern is pretty much the same,
Spoiler (mouse over to view)
the last panel must be the most impact-full. That's why you have characters going to travel in the beginning of the last chapter and returning after a time-skip in the last panel of said chapter. It's just that it's a thing they do to sell more, to let the readers wondering what's next, in fact I prefer definite endings unlike these but we have to make do with what we get.

Regarding the manga, it was really good. If you are tired of those "kids" romances, this is a must. It involves the working society, characters actually make sense and their relationships are well thought out, there's some convenient things happening here and there but you can see past it without problem.

There's sex in it, but I assure you it really must be in it, it's not those ecchi, smut ones it's made naturally in here without exaggerating. It's just this is Seinen and adults... well have sex so better deal with it whoever is a puritan.

... Last updated on October 19th, 2017, 4:23pm
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Rushed ending.   
Rating: 10.0 / 10.0
by darkx
February 14th, 2017, 7:51am
Story's great. Ending was rushed -- not due to the author's plans, rather as others have noted the magazine stopped being published. I still recommend this story to anyone who likes a good romance drama.
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Good manga overall   
Rating: 8.0 / 10.0
by SangMo
October 18th, 2016, 9:55pm
Ending needed more because it was kinda vague, but from what I heard the magazine it was featured in was shutdown so the author decided to wrap it up instead of finding a new magazine.

My interpretation of the ending:
Spoiler (mouse over to view)
When she comes back at the end, she's going to be with them in a polygamous relationship because it was hinting at that heavily especially since they had the threesome. Asou became accepting of Rena being part of her and Aizawa's relationship and came to love her.
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Rating: 8.9 / 10.0
by SilentFaltrnLesrWatr
April 24th, 2016, 3:57am
I'm keeping the high rating because the romance and dialogue was very sophisticated, how all the characters conveyed their feelings and how the story always had a interesting element.
[in spoiler just in case]
Spoiler (mouse over to view)
the end... what a way to ruin something! BOO!! is what I said.. geez. Terrible. Abrupt and stupid! After all that build up and THE ENTIRE THEME! is just.. meh. I mean come on! "I'm leaving" "ok that's fine" was what he said but even worse than that. He had no explanation. And she comes back but after 10 years!!! I thought the title of this story was perfect and cute and tasteful but the ending ruined that completely because I don't know what happened with Rena after that. Basically the theme was cast aside. Oh and the sex was for the most part unromantic and almost trying to be comedic which I'm not really into. But there were other elements I loved about the story and that's why I gave it a high rating to begin with.
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Rushed ending because magazine was cancelled   
Rating: 7.0 / 10.0
by gainare_tottori
December 23rd, 2015, 5:50pm
The ending is abrupt, but it wasn't really the author's fault: the magazine this was in got cancelled and it was too close to his planned ending to get picked up by another magazine. So he just had to wrap it up in the time he had left.
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Don't like the ending entirely   
Rating: 3.0 / 10.0
by HE911
December 18th, 2015, 11:51pm
I really, really enjoyed the series but the ending chap 94-95 really?! The author could have done at least 5-10 more chapters and ended it well. Now I am just left with a sour taste in my mouth... I so wanted to love this 100% of the way but I feel this series has failed me! I've read all of the authors other works and this one ended so poorly Grrrr! I wont give any spoilers. /sigh (╯°□°)╯︵ ┻━┻)
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Rating: 10.0 / 10.0
by wallyakazukin
October 15th, 2015, 5:08pm
Aside from whether Rena's disease is a pure fiction, I like how the characters deal with it. This manga indeed contains adult materials, but they're not mind-wrecking. Instead, it's kinda encouraging, slice-of-life things. The idea is so original. The plot is solid and awesome. Rena who can't live without Agawa's kiss, even though they don't love each other. And Asou, Agawa's girlfriend who has to deal with Rena. How Asou-Agawa's love development despite Rena's problem. How Rena deal with her family and her dream-boy (which is, thank god, not Agawa) about her disease.Everything's wrapped beautifully.
Asou is a great woman, and she's my favorite character here smile
Anyway, if you're 18+, fine with some nudity, and tired of stupid smut or shallow shoujo ordinary plot, I highly recommend this manga. Super interesting.
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Best since "Strawberry 100%"   
Rating: N/A
by cecropiamoth
February 25th, 2013, 10:50am
Both manga have the terrific quality of showing us highly believable, somewhat idealized relationships. Of course the semi-lolicon subplot in this one is absurd, but the depth of understanding of the amazing messes that people can get into when they're trying to work out a relationship is as spot on here as it was in "Strawberry". The only difference is that "Strawberry" had younger characters

As for the semi-loli subtext, well, having it in there is just another example of the unique genius of manga, IMHO. Having read literally thousands of manga, I've come to realize that having an element in the story that's JUST over the line of standard morality is the genius of this form.

Cartoons with titillation. It's a brilliant combination! The use of cartoons is a great advantage for the storyteller because it make it possible for him to present impossibly beautiful people and impossible adventures. The addition of slightly transgressive titillation elements in turn makes up for the one great drawback of cartoons -- there can't be enough text/conversation in them to fully convey the characters' feelings and thoughts and by doing so hold the interest of a smart and/or adult reader.

This is one of the best manga I've ever read. As far as I'm concerned it shows how amazingly much truth about human feelings a cartoon medium can convey.

... Last updated on February 25th, 2013, 1:01pm
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Rating: 8.5 / 10.0
by Jalapeno-san
September 2nd, 2012, 4:13am
at first the plot seemed ridiculous but it was surprisingly good...
I want to see how this end... Rena x Amagi seems pretty "obvious" so I hope that's not going to happen.
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every man's dream, sorta   
Rating: N/A
by pxhai
May 30th, 2012, 2:04pm
kudos to the manga-ka. Some serious shits here to get away from the overwhelming amount of wimpy romantic shounen. Quite a strange way to form an awkward triangle. And horny situations bigrazz. Really curious about the ending, as I read the raws but didn't comprehend what happens at the end.
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