In the future, mankind has fallen into corruption and degradation. In a world slipping slowly into madness, sexual depravity and violence have become the norm. Violent times call for violent responses and now only a shadowy organization of inhuman godly beings, The Committee, has begun to rein in a world of decay. But in order to save the world? Or to satisfy their own twisted desires? No one can tell. Isane is one of their agents, a top Mediator with a mutant arm genetically re-engineered by the council to ‘purge’ the brains and 'cleanse' the blood of the evil and impure...

'Isane -Hound-' and 'Isane -Break Away-' were officially published in North America by Eros Comix from 2003 to 2006 as a series of comics titled 'Sex Warrior Isane Extreme' and 'Sex Warrior Isane XXX'.