New York, 1931. The manufacture and sale of alcoholic beverages is prohibited by law, but behind this prohibition, organized crime flourishes-so, too, do bank robbers, bootleggers, assassins, and homunculi...

By the order of Shogun Ieyasu Tokugawa, ten ninja from the Iga and the Kouga clans must fight to the death in order to determine who will be the next Tokugawa Shogun, with the surviving clan ruling for the next...

The mighty Medicine Faction has fallen to the evil hands of the Venom Clan. As they travel across the land, taking out each clan under the faction, Zhen Ziqiang becomes a test subject for the Elder of the Venom...