Mysterious alchemist Lorenzo Lusignano, descendant of the royal family of Cyprus, is searching for the ultimate secret of alchemy – the Philosopher’s stone "Elixir." Rumors of this blood-red gem creep everywhere, but nobody seems to have seen it, so Lorenzo’s travels through Europe’s Renaissance are never easy.

Each volume has a different title:

1. Guranashisu no Meikyuu (柘榴の迷宮; Granacis Labyrinth)
2. Bara yori mo Akaku Yuki yori mo Shiroku (薔薇よりも赤く雪よりも白く; Redder than Roses, Whiter than Snow)　
3. Gothic Anatomia　(ゴシックアナトミア)
4. Ofiukusu no Keifu (オフィウクスの系譜; Lineage of Ophiuchus)
5. Sen no Yoru no Ryojin　(千の夜の旅人; Traveler of a Thousand Nights)
6. Rakuen no Kizu　(楽園の疵; The Scars of Eden)
7. Chinmoku no Shima　(沈黙の島; Island of Silence)
8. Suijou no Meiro　(水上の迷路; Aquatic Maze)
9. Death Stalker (デス・ストーカー)
10. Seichi 1187　(聖地1187; Holy Land 1187)
11. Kurowashi no Keifu　(黒鷲の系譜; Lineage of Kurowashi)
12. Elixir (エリキサ－; Elixir)
13. Hatami Yo (二十三夜; 23 Nights)
14. Akai Seihai (赤い聖杯; The Red Chalice)
15. Meifu no Zakuro (冥府の柘榴; Pomegranate from the Netherworld)
16. Tenkuu no Shiro (天空の城; Castle in the Sky)