It's the year 2034 and high school student Sasaki Hiiro boards his bus just like any other day. Everything changes, though, when his bus is suddenly attacked by a mysterious girl with red eyes. When Hiiro awakes, he finds himself in "Tokyo," a city which was supposed to have been permanently sealed off after the outbreak of the deadly Pandora Virus ten years ago. Not only that, but it also seems like all those being gathered in "Tokyo" are developing new inhuman abilities. Now, among the ruins of Shibuya, Hiiro and his friends must discover why they are here and learn all they can about the terrible Malicious Code that is running wild in their bodies before it destroys them all!