From Shoujo Yuri Manga Guide:
The main characters are Yajima Junko (Yaji-san) and Shinokita Reiko (Kita-san), two lively high-school girls. They are both very beautiful and very good at fighting with various styles and techniques. They also have a strong sense of justice, and can't stop themselves from helping weak people in need. They are always transferring from one school to another – because every new school they join turns out to be riddled with bad guys (violent gangs, sadistic teachers), and, well, it's always the same thing: by the time they have finished "cleaning up" the place, they have caused so much trouble and angered so many big honchos that they have to leave or be expelled.

Note: The manga was initially serialized in Bonita from the September 1982 issue until 1991. It continued to be serialized in Mystery Bonita from the January 2004 issue on December 6, 2003, to the March 2006 issue on February 6, 2006. The first 22 volumes were published by Akita Shoten between 1983 and 1991; volumes 23 through 29 were published from 2004 to 2006.