Biblia Koshodou no Jiken Techou is a mystery series in which Shinokawa Shioriko, a young owner of a bookstore in Kamakura, unravels the mysteries of the ancient books that are taken there.

The story begins with a young man named Daisuke, who practically grew up without reading books due to his phobia, who brings the complete (and autographed) collection of works by Natsume Soseki, (Japanese writer of the Meiji era) that he inherited from his grandmother, to the mysterious bookstore. Will the shy and introverted Shioriko solve the mystery of the books?