From Kodansha:
When Setsu's grandfather died, so did Setsu's "sound" - his unique creative spark. Grieving, he goes to Tokyo to find himself but manages to become totally, literally lost on his first day. Only a chance meeting with Yuna - aka Yuka, the hostess - saves him from being robbed. At first glance, their lives seem totally different but they're both striving for their dreams. Hers, of being an actress, and his, of developing his talent with the shamisen and it could just be that life in the raucous, unfeeling urban sprawl of Tokyo could just be what binds their fates together.

Official English