Something like Ani no Yome to Kurashite Imasu.. Love So Life kinda counts, just because i know someone is going to mention it. Not looking for anything with live in lovers and dead parents is not a must. Demografic doesnt matter.

"The oldest and strongest emotion of mankind is fear, and the oldest and strongest kind of fear is fear of the unknown"

Hinamatsuri is about an orphaned girl moving in with a yakuza guy as her surrogate father, Chichi to Hige Gorira to Watashi is about a guy moving in with his widowed brother and his daughter.