Urasawa. If your jaw doesn't drop after hearing that name, you've obviously been reading the wrong manga my friend.
I'll admit, the hype for this series was too intimidating for me to go near it. In fact, I'm glad I avoided it for so long until I was psychologically prepared for it.
If I'd have to start with this manga, I'd have to applaud the author on his brilliantly coordinated narrative. An aptitude for developing his own sense of thriller, this gets thrown on top of horror lists next to Ripley Scott's feature film "Alien" and John Carpenter's "The Thing". It takes a while to pick up what devices the author uses, but you soon realize every character Dr. Tenma encounters develop 3-Dimensional character traits. With that as his basis, the author freely switches perspectives revealing trails that lead to either Dr. Tenma or Johan, and thus the plot thickens.
The bad guy, Johan, is the most evil character in all the manga series that I know, and I know them all. The author toys with rationality as he creates a smart, handsome and smiling young man with all the desire to destroy everything he comes in contact with. The discretion in Johan's actions build his character in our minds as the most evil person you will ever see. The tips and hints the author has so cleverly thrown in to the dialogue all revert back to a single name, and even though they don't know who they're looking for, we always know it's Johan.
Dr. Tenma is one of the most modest people we know in this series, as most Japanese residing in Germany at that time were. He never blames anyone but himself in this series, and that's because most of the time he believes it's his fault that this "Monster" was unleashed upon the world. It is then that this magnificent story unfolds, starting with a race of people chasing other people, knowing everyone's motivations and their exaggerated, but metaphorical methods. Dr. Tenma always remembers that it's in his blood to save lives and not destroy them at any cost, even if it means taking another man's life. But that ultimately causes his hesitation and stops him when he always has the chance.
Throughout the series it's been a roller coaster as we dig deeper and deeper into the mind of a monster, trailing behind him and learning of his goals. We piece together his ambitions in each subplot, expanding his ever-growing picture of a Utopia. We learn how it must feel tracing back the devil's handy-work. The author teaches us that there's only one thing that must be done if you saw a killing machine on the loose, and that's to stop it.
Overall, the best read I could've possibly picked up. One of the things I loved whenever I read the series was the many times Johan's name is mentioned, you suddenly want to pay attention and understand that sometimes the ends can justify the means. A masterpiece. One could say the best work from Urasawa thus far.