I'm looking for manga with the main charcter either being

1. MR (Mentally Retarded, not the shonen stupid kind, actual MR)

2. Physical Disabilites

3. Austim (Asperger as well).

4. Other mental disabilites

Along these general lines. I would really like to read some...
Like IS, where they are struggling with their disorder/disability.

I looked around and didn't find anything like this so sorry if there is one already.

"I've seen a look in dogs' eyes, a quickly vanishing look of amazed contempt, and I am convinced that basically dogs think humans are nuts." -John Steinbeck

2. REAL

Nodame imo
Cat Street
Change 123

To help start you off.

2. Physical Disabilities.

Hope it helps~

With the Light

These might help too:
manga with disabled characters
OCD
visually/verbally impaired

Looking for... shoujo with a canned peach confession. Don’t English me I’m panic.

Limited lovers quite an interesting shoujo bout a doctor and a girl with a physical disability..
also try reading Fetish, Shigeshoushi,Franken Furan, Present and DOLL: IC in a doll..the plot of these mangas revolve around physical disabilities like blindness, disabled characters and also psychological illness.. but they're presenting these in a different context than I.S

Also, try reading Hana no namae and Brigit's dinner

[img]http://i268.photobucket.com/albums/jj11/obinrobin31/FINISHED2-Roger.gif[/img]
[color=black]The Hidden Agenda=[/color][color=red]Gol.D.Ace[/color]

[color=black]This Week's favourite:[/color]
DoLL (Okado Tatsuya)
Xp

Nodame is not really mentally impaired. She is just a weirdo.

Try Kingyo Sou? The male lead is deaf.

Also, in Shikeishu 042, the female lead is blind.

Avatar by tassyn.livejournal.com

Reading: Kingdom, Sangokushi, Historie

@oriana3k
I can't believe there actually is a manga about autism 😲

I knew there would be more about physical than mental.
I'd still want to know if there's one about MR, that's what I'm really interested in.

I make a lot of odd requests so thank you all for not getting annoyed and hunting me down and actually helping 🤣

"I've seen a look in dogs' eyes, a quickly vanishing look of amazed contempt, and I am convinced that basically dogs think humans are nuts." -John Steinbeck

Freesia is about a guy who's struggling with insanity, actually most of the characters are. It's a great read if you don't mind a bit of blood.

Probably an obvious one, but Welcome to the NHK! is as good an exploration of mental illness/ depression as I've found. For some reason they put cute girls on the cover and sell it as some crazy perverted stoner trip or whatever, but it's a bit more subtle and depressing (as well as funny) than that.