Basically what the title says, perfer it to have some comedy and a romantic subplot.

Obvious examples are Trigun and Witch Hunter

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"Religion is like a gun, It's only as good as the people holding it and it can easily take a life."

-Personal thought

I think this is a repeat thread.

Chrno Crusade
Hellsing
Tegami Bachi
Gunslinger Girl
Mother Keeper
Ao no Exorcist Not the main protagonist.
Red Eyes
Dogs: Bullets & Carnage
Fate/Stay Night dj - Magic Gunner Rin Trololol
Grenadier
Deus Ex Machina
Kurohime
Shikabane Hime
Golgo 13
Cowboy Bebop
Black Lagoon
Hidan no Aria
Angel Beats! - Heaven's Door
Akumetsu This dude uses everything, but read it anyways.
Highschool of the Dead Of course.

Take note that I included non-supernatural guns, which seems to be what you're looking for.
Just what I could come up with off the top of my head.

Last edited by Dafat-MKII at 3:49 pm, Mar 23 2011

hope you will like this one, its really good in my opinion Jormungand

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"I dont belive an eye for an eye, i belive in two eyes for an eye!"

- Bas Rutten

Black Cat

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Mittsu no kokoro ga hitotsu ni nareba...
Hitotsu no seigi wa hyakuman pawaa.
- Getter Robo -