I am in search of manga where best friends (guy/girl) end up together.

They can be childhood friends, but it's not a requirement.

I'd prefer the male pov, but it's not a requirement.

Not 100% sure if they do end up with each other but they are the main focus
Balls Friend
Our Relationship Is...
Boku Girl

These ones are definite:
Gacha Gacha - Capsule (sort of?)
Horimiya
Kanojo ni Naru Hi
Ojojojo
Wotaku ni Koi wa Muzukashii

There's also the tag 'Friends becomes Lovers' which you might want to look up.
Hope you enjoy them! 😀

Asleep

Ai Yori Aoshi > Kind of
Amagami - Precious Diary
Beast Master
Cross Game
D-ASH
Fullmetal Alchemist
Ga-rei
GE
Ginen Shounen
Hajimete Datteba!
I"s
Kirara
Love Hina
Mademoiselle Butterfly
Max Lovely!
Milk Crown
Open Sesame
Orange Yane no Chiisana Ie
Parallel
Rave
Suzuka
Zero In

All of the above have what your looking for in some form or another.

This is my Sig ..............................................................

Most of these are gonna be shoujo or josei, so girl PoV, but I'll list them anyway. (also I've been reading a lot of web comics lately)

14-sai no Koi
Kakao 79%
Tomo-chan wa Onnanoko!

Maybe Fits
Love Com
Last Game
ReLIFE
Unlucky Mansion
Oh! Lord Jesus (don't be turned off by the title XD)
The Sensual M (don't be turned off by the BDSM tag, it's actually really sweet)
Skip Beat - if you want to strap in for a really long ride that's unfinished, where the relationship is really really secondary to the primary plot.

Seconding
Our Relationship is...
Horimiya
Wataku ni Koi wa Muzukashii