definitely Okami..no question about it
when i first played this game i was soo obsessed that i played non-stop until i finished. and when i finish the game i just keep replaying again and again for 2 years.. I lost count on how many times i finish he game.. i think i lost count around 35 or 40

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Psychonauts
Okage
Threads of fate
Baten Kaitos eternal wings and the lost ocean + origins
Skies Of Arcadia

Especially the Baten Kaitos games and Skies Of Arcadia.

I'm playing Resonance of fate right now and its damn good. I already think needs a sequel. I don't care what it's about. There just needs to be more games w/ similar gameplay to this.

Totally agreed with Okami. (But the DS one coming out isn't actually a sequel, is it? I thought it was the same game but just for a different console...have to look into that )

I was extremely excited when I found out they were releasing a third Golden Sun.

A proper "Banjo Threeie" perhaps?! Nuts & Bolts sucked, and the originals were such a big part of my childhood.

I also second "The World Ends With You"!

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Go to work, send your kids to school;
Follow fashion, act normal;
Walk on the pavement, watch T.V.;
Save for retirement, obey the law.
Repeat after me: I am free.

Like many of the other posters have said, I would love an Okami sequel. I'd love to play as Amaterasu again and save the Celestial Plains(heaven) with Waka~
I'd also love to know more about the Lunar tribe.
I know they have 'Okamiden' for the DS, but that feels more like a spin-off than a direct sequel.

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Hogs of War. With not only Rik Mayall, but John Cleese, Tom Baker, Stephen Fry and a host of other British comedians and TV personalities as optional narrarators. Gameplay would be pretty much the same, except with new weapons, more teams, deep map customization, and of course multiplayer modes.

Would easily be the greatest game EVER made!

Shenmue!!!!!!!!!!!!!!!!!!!
Possibly the only and most anticipated sequel for ever DC owner.

Diablo and Dungeon Siege for PC maybe. They have already a trailer and its AAAAAAAAAAWWWWWSSSSSSSSSOOOOOMMMMMMMMM MEEEEEE!

this. I just wish the makers would show any sign of making a another sequel..
but this time I'd like it to be more faithful to its predecessors.
dragon quarter is a decent game by itself imo.
but its still not breath of fire game..