Or if there's a manga where the main leads don't end up together. I don't know any examples...but [m]HYD[/m]. Although Rui isn't the main lead, she actually did like him in the beginning, and then they kind of drifted...
Or Sand Chronicles because
Spoiler (highlight to view)
they broke up
although I don't know what happens in the end..Sorry if this is all confusing, but I was getting sort of annoyed by all the manga where they end up together, when they met in high school, and get married and have kids...I mean, it's not that common is it?
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